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S. V. Drogobuzhskaya, S. E. Kondakov, N. K. Belisheva, A. I. Novikov, E. S. Ihalainen
Comparison of elemental blood analysis in
intact and dry samples. porous membranes as a new sampling format
Abstract
The possibility of using dry blood samples
on porous glass fiber membrane carriers (PGMC) for blood quantitative elemental
analysis of using the method of inductively coupled plasma mass spectrometry
(ICP MS) has been demonstrated. Comparison of the results of elemental analysis
of intact blood and its dry samples is carried out. It was shown that
regardless of the state of the samples (wet and dry), as well as the method of
sample preparation (different volumes of elution solution), the content of the
corresponding elements in dry samples fully corresponds to the content of
elements in whole blood and to the reference values according to literary data.
Key words: DBS technology, new format DBS
cards, fiberglass carrier, whole blood, stripped dry whole blood samples,
inductively coupled plasma mass spectrometry.
Copyright (C) Chemistry Dept., Moscow State University, 2002
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