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S. V. Drogobuzhskaya, S. E. Kondakov, N. K. Belisheva, A. I. Novikov, E. S. Ihalainen

Comparison of elemental blood analysis in intact and dry samples. porous membranes as a new sampling format


The possibility of using dry blood samples on porous glass fiber membrane carriers (PGMC) for blood quantitative elemental analysis of using the method of inductively coupled plasma mass spectrometry (ICP MS) has been demonstrated. Comparison of the results of elemental analysis of intact blood and its dry samples is carried out. It was shown that regardless of the state of the samples (wet and dry), as well as the method of sample preparation (different volumes of elution solution), the content of the corresponding elements in dry samples fully corresponds to the content of elements in whole blood and to the reference values according to literary data.
Key words: DBS technology, new format DBS cards, fiberglass carrier, whole blood, stripped dry whole blood samples, inductively coupled plasma mass spectrometry.
Moscow University Chemistry Bulletin.
2021, Vol. 62, No. 2, P. 145

Copyright (C) Chemistry Dept., Moscow State University, 2002
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