Vladimir Maxovich Morozov

(b. 1966)

CHEMICAL ENZYMOLOGY DIVISION
LABORATORY OF PHYSICO-CHEMICAL ASPECTS OF ENERGY BIOCONVERSION
BIOLUMINESCENCE: PRINCIPLES AND APPLICATIONS
BIOINFORMATICS, COMPUTATIONAL BIOLOGY

EDUCATION:
Master's Degree (excellent) in Chemical Enzymology, 1992, Chemistry Department, Moscow State University.
Graduate Program, 1992-1995, Chemistry Department, Moscow State University. I expect to obtain the Ph.D. degree this year.

RESEARCH AND PROFESSIONAL EXPERIENCE:
1995-present: research engineer, Chemistry Department, Moscow State University
1992-1995: Graduate student, Chemistry Department, Moscow State University
1993-present: reviewer-translator, Russian State Institute of Scientific Information, Computational Biology Division.

AWARDS:
First bonus at student conference in analytical chemistry section (1989).
Second bonus at student conference in enzymology and chemical kinetics section (1990).
The member of Chemistry Faculty Council (student representative), 1989-1990
Lenin scholarship (highest student scholarship in Soviet high education). 1990.
ISF (Soros) Grants, 1994-1995

RESEARCH INTERESTS:
Structure and functional analysis of protein sequences:

  1. determining the function of uncharacterized proteins translated from genomic or cDNA sequences.
  2. functional pattern recognition in family of related protein.
  3. prediction of secondary structure, solvent accessibility and tertiary structure based on sequence homology.
Relevant publications:
  1. V.M. Morozov. Structure and Function Analysis of Amino Acid Sequences via Internet, Molecular Biology (Moscow) 1996, N 2, p. 231-234.
  2. V.M. Morozov, N.N. Ugarova. Conserved Motifs in Superfamily of Enzymes Catalyzing Acyl Adenylate Formation from ATP and Compounds with Carboxy Group (accepted to journal "Biochemistry" (Moscow)).

Also, I apply a new statistical approach to analysis of dependence of functional property on amino acid composition in a peptide set. It is especially promising for identifying key residues (mostly influencing on properties) in random peptide libraries and protein families divided by functional, evolution, or other criteria.

Relevant publications:

  1. V.M Morozov. Localization of protein site responsible for luminescence color in beetle luciferases. In: Bioluminescence and Chemiluminescence: Current Status /Eds. Szalay A. et al. N.Y.: John Wiley, 1994, p. 536-539.
  2. V.M. Morozov, V.V. Ivanisenko, A.M. Eroshkin, N.N. Ugarova. Computer analysis of the dependence of bioluminescence spectra maximum on beetle luciferase sequences: Identification of amino acids responsible for colour differences (accepted to journal "Molecular Biology" (Moscow)).

OTHER PUBLICATIONS:

  1. A.F. Dukhovich, V.M. Morozov, and N.N. Ugarova. Effect of substrates on the stability of firefly luciferase incorporated in phosphatidylcholine liposomes. Biochemistry (Moscow) 57, 1179-1182 (1992).
  2. A.F. Dukhovich, V.M. Morozov, and N.N. Ugarova. Modulation of lipid-protein interactions in firefly luciferin-luciferase system by substrate adenosine 5'-triphosphate. Membr. and Cell Biol. 8, 643-650 (1995).

ADDRESS:
Chemical Enzymology Division, Chemistry Department,
Moscow State University, Moscow, 119899 Russia
PHONE: 7(095) 939-2652
FAX: 7(095) 939-2742
MOROZOV@ENZYME.CHEM.MSU.SU


Webmaster@www.chem.msu.su